This is a hormone that helps the body to manage the endocrine system by impacting cell proliferation and neurotransmission by interacting with somatostatin receptors (G protein-coupled) to inhibit the release of secondary hormones throughout the body.
There are two active forms that are often produced by preproprotein, one containing 28 amino acids and one that contains 14 amono acids. Vertebrates have six different genes that participate in somostatin production, allowing it to perform a variety of functions depending on the animal in which it is displayed.
Somatostatin may be produced in an animal’s digestive system to encourage acid producing parietal cells while decreasing production of histamine, gastrin and secretin. It is also present in the gastrointestinal system to stop the release of overactive gastrointestinal hormones to suppress pancreatic hormones or decrease the rate in which the gastric system empties while improving blood flow to the intestines.
This is classified as an inhibitory hormone which can be spread to many other areas of the body in an animal, particularly in inhibiting the release of thyroid stimulating hormone.
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